During the last decades, Solid Phase Peptide Synthesis has grown steadily to become the most popular way of synthesizing small quantities of peptides.   Indeed, in most cases, milligram to gram scale quantities of most peptides can be produced very quickly and cost effectively, making SPPS the method of choice for producing the quantities required at the early phase of a peptide project.

SPPS also remains the optimal production method for commercial quantities of some peptides, especially in the case of relatively long peptide sequences (over 20 amino acids).  

Even though SPPS represents per se a generic method of making peptides, many different variants (to name but a few, Boc or Fmoc chemistries, specific protecting groups, specifically designed solid supports …) have been developed over the years.  Finding the best method for producing a given peptide sequence up to kilogram quantities requires an extensive know how.   Peptisyntha relies on a group of experts having decades of experience with all aspects of SPPS, from the synthesis of milligram quantities up to the production of kilogram quantities under cGMP conditions.